Y Combinator Startup Podcast Transcripts
Y Combinator · 331 episodes with transcripts
We help founders make something people want. The Y Combinator Podcast is where builders talk about building. From the earliest days of an idea to scaling a company that changes the world, YC partners and founders share real stories, lessons, and tactics from the frontlines.
Spoken has transcripts of 331 Y Combinator Startup Podcast episodes, with the speakers named. The newest listed here is from September 26, 2026.
Every Y Combinator Startup Podcast transcript in one script
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Latest Y Combinator Startup Podcast transcripts
Robot-Use Agents: Why General-Purpose Models May Win in Robotics
September 26, 2026
Francois (0:00)
One of the big surprises the last few years has been the generalizability of coding agents across different domains. And now Frontier researchers are showing that this includes controlling robots. This led MIT professor Philip Isola to suggest in a recent viral essay that we may be entering the era of robot use…
Maybe you guys want to briefly introduce yourselves, and just say a little bit about what each of your companies focuses on.
Hanmei (0:40)
I'm Hanmei. I'm from Waddle Labs together with Vincent. We work on building LLMs that control robots, and we do this by doing two things. Building a harness that allows the LLMs to do this very effectively, collecting data and then using that data to train better LLMs.
Jay (0:54)
Hi, I'm Jay, co-founder of RoboCurve.
We are an evalus company for physical AI. We measure everything, any robot, any model, including LLMs, and also classical approaches such as VLAs, Vision Language Action Models, and Word Action Models, and we evaluate all kinds of embodiments like hands, grippers, arms, humanoids, quadrupeds, all kinds of stuff.
- Robot-Use Agents: Why General-Purpose Models May Win in Robotics
- The State of Startups in 2026
- 8 Ways To Improve Your Outbound Sales
- Open Models Change The Economics of AI
- Paul Graham On Startups, Ambition, and Great Founders
- The World’s Largest Electric Aircraft Just Flew
- Max Junestrand: You Need The Willingness To Learn Faster Than Anyone Else
- Susan Kare: Designing Icons & Graphics For the Original Mac
- Chelsea Finn: This is the State of the Art in Robotics
- Peter Steinberger: "Fun Is Velocity"
- Max Hodak: How Startups Build Speed
- How To Design In The Agent Era
- Garry Tan: Own Your Intelligence
- Building the First Data Centers in Space
- Waymo Co-CEO Dmitri Dolgov: "Move Fast And Ship Safely"
- Patrick Collison: "What If You Succeed?"
- Jeff Dean: The 1% Rule for Building in AI
- Alexandr Wang: “This is a Once-in-a-Civilization Opportunity”
- Blake Scholl: Breaking the Supersonic Ban
- Sam Altman: "Never a Better Time to Do a Startup"
- Boris Cherny: Building Claude Code
- Jensen Huang: The Mindset That Built NVIDIA
- World Models, Explained
- How To Better Understand Your Users
- Why Domain Experts Are Winning In The Age Of AI
- How To Pick A Startup Idea
- "The CEO Must Be the Chief AI Officer"
- How to Build an AI-Native Services Company
- How To Build Superintelligence Inside Your Company
- How The Best Companies Defend Against Mediocrity And Rot
- Paul Graham: Should you move to Silicon Valley?
- Tokenmaxxing: How Top Builders Use AI To Do The Work Of 400 Engineers
- Beyond Bigger Models: Recursion As The Next Scaling Law In AI
- The $9B Startup That Wants to Create a Billion New Developers
- The Playbook For Building An AI Native Company
- Stripe Head of Design Katie Dill Breaks Down Their New Website
- This Startup Wants To Catch Cancer Before It Spreads
- This Startup Secretly Detects Fraud For Fortune 500s
- How François Chollet Is Building A New Path To AGI
- Inside The Startup Reinventing America’s Trillion Dollar Chemical Industry
- Building A Global AI Startup From India
- The Future Of Brain-Computer Interfaces with Science's Max Hodak
- How To Avoid AI Design Slop
- The Fastest Path To Super Intelligence
- The AI Agent Economy Is Here
- Inside Claude Code With Its Creator Boris Cherny
- The New Way To Build A Startup
- OpenClaw And The Future Of Personal AI Agents
- We're All Addicted To Claude Code
- How To Get Your First Customers
- Inside The Startup Building Reusable Rockets
- What Surprised Us Most In 2025
- How Intelligent Is AI, Really?
- The End of the Designer–Engineer Divide
- From Pivot Hell To $1.4 Billion Unicorn
- The Best Consumer Startup Ideas Were "Impossible" Until Now
- Cursor Head of Design Reviews Startup Websites
- Inside The Startup Launching AI Into Space
- How To Recruit The Best Engineers And Sales Reps
- From Idea to $650M Exit: Lessons in Building AI Startups
- Transformers: The Discovery That Sparked the AI Revolution
- YC Partners Answer Your Questions | Office Hours
- What Everyone Is Getting Wrong About AI And Jobs
- How To Design Products That Truly Stand Out
- The World's First Commercial Mobile Carbon Capture Device
- Every AI Founder Should Be Asking These Questions
- Anthropic Head of Pretraining on Scaling Laws, Compute, and the Future of AI
- Fintech 3.0: Now Is The Best Time To Build In Crypto
- Aaron Levie: Why Startups Win In The AI Era
- The Future of Software Creation with Replit CEO Amjad Masad
- The FDE Playbook for AI Startups with Bob McGrew
- Michael Truell: Building Cursor at 23, Taking on GitHub Copilot, and Advice to Engineering Students
- GPT-OSS vs. Qwen vs. Deepseek: Comparing Open Source LLM Architectures
- How This 25-Year-Old Built A $675M Legal AI Startup (With No Legal Experience)
- The Sales Playbook for Founders | Startup School
- Figma CEO Dylan Field: How AI Will Transform Design
- The Finance Startup Bringing Agentic AI to Wall Street
- Scaling and the Road to Human-Level AI | Anthropic Co-founder Jared Kaplan
- Brand Design Tips From Linear Founder Karri Saarinen
- Chelsea Finn: Building Robots That Can Do Anything
- Replit CEO Amjad Masad: Coding Agents, Autonomy, and the Future of Work
- John Jumper: AlphaFold and the Future of Science
- Aravind Srinivas: The Race to Build the AI Browser of the Future
- Andrew Ng: Building Faster with AI
- François Chollet: The ARC Prize & How We Get to AGI
- Fei-Fei Li: Spatial Intelligence is the Next Frontier in AI
- Legendary Consumer VC Predicts The Future Of AI Products
- Satya Nadella: Microsoft's AI Bets, Hyperscaling, Quantum Computing Breakthroughs
- Sam Altman: The Future of OpenAI, ChatGPT's Origins, and Building AI Hardware
- Elon Musk: Digital Superintelligence, Multiplanetary Life, How to Be Useful
- Andrej Karpathy: Software Is Changing (Again)
- Cursor CEO: Going Beyond Code, Superintelligent AI Agents And Why Taste Still Matters
- Fusion Energy Is Tech's Next Big Unlock
- AI Apps Are Broken — Here's How To Fix Them
- How AI Coding Agents Will Change Your Job
- How To Get The Most Out Of Vibe Coding | Startup School
- How Zepto Became India’s Fastest Growing Startup
- Why America Stopped Innovating - And How We Can Start Again
- What Founders Can Do To Improve Their Design Game
- How to Build the Future: Tony Xu
- Customer Obsession Made Gusto A $9.6 Billion Company
- The Future Of Design With Figma's Dylan Field
- How To Build The Future: Aravind Srinivas
- Building A Supersonic Plane Company From The Ground Up
- The Right (And Wrong) Way To Spend Money At Your Startup
- How To Build The AGI Future: Bob McGrew
- How To Use AI In Your Startup
- How To Build The Future: Parker Conrad
- Building A $2 Billion SaaS Company: Lessons From A Two Time Founder
- How David Lieb Turned A Failed Startup Into Google Photos | Backstory
- How To Start A Dev Tools Company with Nicolas Dessaigne | Startup School
- Twitter vs. X: Product Lessons For Startup Founders | The Breakdown
- How To Build The Future: Sam Altman
- How Do Billion Dollar Startups Start? | Office Hours
- Why Design Matters: Lessons from Stripe, Lyft and Airbnb | Design Review
- How To Find A Co-Founder with Harj Taggar | Startup School
- How To Convert Customers With Cold Emails with Aaron Epstein | Startup School
- How To Improve Cohort Retention with David Lieb | Startup School
- Co-Founder Equity Mistakes to Avoid with Michael Seibel | Startup School
- How Nothing Founder Carl Pei Built A Multi-Million Dollar Smartphone Brand In Just 2 Years | Main Function
- How To Price For B2B with Tom Blomfield | Startup School
- Why Startup Founders Should Launch Companies Sooner Than They Think | Office Hours
- Enterprise Sales with Pete Koomen | Startup School
- Startup Experts Discuss Doing Things That Don't Scale | Office Hours
- How to Survive the Crypto Boom & Bust Cycle | Main Function
- Consumer Startup Metrics with Tom Blomfield | Startup School
- When Should You Trust Your Gut? | Dalton & Michael Podcast
- Building Confidence In Yourself and Your Ideas | Dalton & Michael Podcast
- Stop Innovating (On The Wrong Things) | Dalton & Michael Podcast
- Should Your Startup Bootstrap or Raise Venture Capital? | Dalton & Michael Podcast
- How To Build A Tech Startup With No Technical Skills | Dalton & Michael Podcast
- B2B Startup Metrics with Tom Blomfield | Startup School
- Should You Be Optimistic About The Future of Technology? | Dalton & Michael Podcast
- AI and the Future of Law: The 10 Year "Overnight" Success Story | Main Function
- How To NOT Get Screwed As A Software Engineer | Dalton & Michael Podcast
- Should You Quit Your Job At A Unicorn? | Dalton & Michael Podcast
- Does Your Startup Need To Be In San Francisco?
- Will OpenAI Kill All Startups?
- Silicon Valley's Cargo Culting Problem
- Setting KPIs and Goals with Divya Bhat | Startup School
- Tips For Technical Startup Founders | Startup School
- Secrets You Can Learn From Your Customers
- Inside The Most Powerful Startup Community In The World
- How Startup Fundraising Works with Brad Flora | Startup School
- How to Build An MVP with Michael Seibel | Startup School
- How To Earn Customers For Life
- The REAL Potential of Generative AI
- The Hard Conversations Founders Don't Want to Have
- The Best Way To Launch Your Startup with Kat Mañalac | Startup School
- Advantages Of A First-Time Founder
- The Cult of Conformity in Silicon Valley
- Don't Make These Hiring Mistakes
- Keys To Successful Co-Founder Relationships with Cat Li & Divya Bhat | Startup School
- How To Compete With Amazon and Google
- The Secrets To Setting Smarter Goals
- Investors Said No, Now What?
- When to Launch Your Startup and When to Wait
- How to Get Your First Customers with Gustaf Alströmer | Startup School
- Startup Business Models and Pricing with Aaron Epstein | Startup School
- How to Talk to Users with Gustaf Alströmer | Startup School
- Should You Start a Startup? with Harj Taggar | Startup School
- Avoid These Tempting Startup Ideas
- The Truth About Y Combinator
- The Two Mindsets That Can Kill Your Startup
- What Basic Game Theory Teaches Us About Startups
- Most Important Lifestyle Habits Of Successful Founders
- Elon Musk & The Midwit Meme
- Things That Don't Scale, The Software Edition
- Why Investors (including YC) Can’t Fix Your Company
- What Does It REALLY Mean To Do Things That Don't Scale?
- How To Change The World? Get The Small Things Right
- Simple Products That Became Big Companies
- Where Do Great Startup Ideas Come From?
- Successful Founders Are OK With Rejection
- Should You Follow Your Passion?
- YC Founders Made These Fundraising Mistakes
- YC Founder Firesides: Gusto on building for new verticals
- Co-Founder Mistakes That Kill Companies & How To Avoid Them
- Dealing With Setbacks And The Startup Gut Punch
- Saving Your Startup During an Economic Downturn
- Why You Should Leave Your FAANG Job
- How Future Billionaires Get Sh*t Done
- #157 - Diego Saez Gil
- #156 - Amber Atherton and Iba Masood
- #155 - Laks Srini
- #154 - Matt Cutts
- #153 - Cory Doctorow and Joe Betts-LaCroix
- #151 - Startup School Week 10 Recap - Ali Rowghani on How to Lead and Kevin Hale and Adora Cheung on Startup School 2019 by the Numbers
- #150 - Startup School Week 9 Recap - Carolynn Levy on Modern Startup Financing and Jared Friedman’s Advice for Hard-tech and Biotech Founders
- #149 - Startup School Week 8 Recap - Adora Cheung on Prioritizing Your Time and Kevin Hale on Evaluating Startup Ideas
- #148 - Startup School Week 7 Recap - Kevin Hale on Conversion Rates and Pricing
- #147 - Startup School Week 6 Recap - Tim Brady on Culture and Dalton Caldwell on Pivoting
- #146 - Startup School Week 5 Recap - Kirsty Nathoo and Kevin Hale
- #145 - Startup School Week 4 Recap - Kat Mañalac and Gustaf Alströmer
- #144 - Startup School Week 3 Recap - Anu Hariharan and Adora Cheung
- #143 - Startup School Week 2 Recap: Michael Seibel, Adora Cheung, and Ilya Volodarsky
- #142 - Startup School Week 1 Recap: Kevin Hale and Eric Migicovsky
- #141 - Diana Hu
- #140 - Aaron Harris on Fundraising and Meeting with Investors
- #139 - Jay Reno
- #138 - Russ Roberts
- #137 - Startup School Podcast Preview with Kevin Hale
- #136 - Anu Hariharan on Managing a Board
- #135 - Camille Fournier
- #134 - Sarah Nahm and Holly Liu
- #133 - Updates for Startup School 2019 and Office Hours with Kevin Hale
- #132 - Dan Hockenmaier and Gustaf Alströmer
- #131 - Jeremy Rossmann
- #130 - Tracy Young and Kat Manalac
- #129 - Simone Giertz
- #128 - Michael Babineau and Kevin Hale
- #127 - Vidit Aatrey and Adora Cheung
- #126 - Chris Best and Jonathan Gill
- #125 - Brian Halligan and Kevin Hale
- #124 - Jarvis Johnson
- #123 - Harry Zhang and Kevin Hale
- #120 - Austen Allred
- #119 - Amy Buechler and Michael Seibel
- #118 - Marques Brownlee
- #117 - Craig Cannon and Adora Cheung
- #116 - Domonique Fines and Cadran Cowansage
- #115 - Mike Knoop and Kevin Hale
- #114 - Karn Saroya
- #113 - Caterina Fake and Kat Manalac
- #112 - Ryan Hoover and Dalton Caldwell
- #111 - Jake Klamka and Kevin Hale
- #110 - Avni Patel Thompson and Kat Manalac
- #109 - Samantha Bradshaw
- #108 - Cindy Mi and Qi Lu
- #107 - Vinod Khosla and Sam Altman
- #106 - Frank Lantz
- #105 - Reham Fagiri and Kalam Dennis
- #104 - Leonard Susskind
- #103 - Michael Seibel
- #102 - Andrew Kortina
- #101 - Brian Donohue
- #100 - Sam Altman
- #99 - Laura Deming
- #98 - Shola Akinlade
- #97 - David Hua and Vincent Ning
- #96 - Mathilde Collin
- #95 - Eli Schwartz
- #94 - Joan Lasenby
- #93 - Peter Reinhardt
- #92 - Ryan Petersen
- #91 - David Zeevi
- #90 - Jessica Brillhart
- #89 - Geoff Ralston and Adora Cheung Discuss Startup School
- #88 - Office Hours with Michael Seibel
- #87 - Elad Gil
- #86 - Jocko Willink and Mike Sarraille
- #85 - YC Partner AMA at the Female Founders Conference
- #84 - João Batalha and Luís Batalha
- #82 - Henrique Dubugras of Brex and Anu Hariharan
- #81 - Announcing Work at a Startup
- #80 - Office Hours with Adora Cheung
- #79 - Liz Wessel
- #77 - John Preskill
- #76 - Carola Schönlieb
- #75 - Sean Mitchell
- #74 - Linda Xie and Avichal Garg
- #73 - Patrick Moberg and Holly Liu
- #72 - Miles Brundage and Tim Hwang
- #71 - Claire McDonnell and Jennifer Kim on Building an Inclusive Company Culture
- #70 - CoinList Cofounder Andy Bromberg and Ramon Recuero
- #69 - Anne Wojcicki of 23andMe and Sam Altman
- #68 - Cost vs Quality in Edtech - Keith Schacht, Avichal Garg, and Geoff Ralston
- #67 - 3D Home Printing for the Developing World - Alexandria Lafci and Brett Hagler of New Story Charity
- #66 - Breaking Down HackerRank's Survey of 40,000 Developers with Vivek Ravisankar
- #65 - Funding Is an Outcome of Building a Good Business - Porter Braswell of Jopwell
- #64 - Researching Psilocybin's Effects on Depression - Dr. Rosalind Watts
- #63 - The Number One Goal is Getting Started - Avni Patel Thompson of Poppy
- #62 - Dan Lewis, CEO of Convoy, on the Future of Freight
- #61 - Sam Altman on Masters of Scale
- #60 - Startup Investor School Preview with Geoff Ralston
- #59 - Providing Fair Financial Products for the 56% of the US Without Access to Them - Jake Rosenberg of LendUp
- #58 - It's Surprising How Much Small Teams Can Get Done - Sam Chaudhary of ClassDojo
- #57 - Alex Blumberg of Gimlet Media
- #56 - Leah Culver of Breaker and Tom Sparks of YC Answer Your Questions About Security and Podcasting
- #55 - Tim Urban of Wait But Why
- #54 - Growth Office Hours: Round 2
- #53 - Be Wary of Solving a Small, Rare Problem - Des Traynor of Intercom
- #52 - Making Physical Retail as Easy as Opening an Online Store - Ali Kriegsman and Alana Branston of Bulletin
- #51 - There's an Art to Getting Brilliant People to Surprise Themselves - Kevin Slavin of The Shed
- #50 - Growth Office Hours with Anu Hariharan and Gustaf Alstromer
- #49 - Microbes, Robots, and Ambition - Robin Sloan on His Novel Sourdough
- #48 - The Future of Bike Sharing with Ofo Cofounder Yanqi Zhang and Anu Hariharan
- #47 - Baidu's COO, Qi Lu Discusses AI with Daniel Gross
- #46 - Tencent's Chief eXploration Officer, David Wallerstein on WeChat, QQ, and Gaming
- #45 - Building Dota Bots That Beat Pros - OpenAI's Greg Brockman, Szymon Sidor, and Sam Altman
- #44 - Cindy Mi on Building VIPKID, the World's Largest English Learning Platform for Children
- #41 - Experiments in Art and Technology with Artforum Editor Michelle Kuo
- #40 - Content Marketing Tips from Experts at First Round Capital and Andreessen Horowitz
- #39 - Mr. Robot's Technical Producer and Writer - Kor Adana
- #38 - The More You Communicate with Users, the Higher Chance You'll Build Something They Want - Ryan Hoover of Product Hunt
- #37 - Don't Start a Blog, Start a Cult - Mr. Money Mustache
- #36 - Your Whole Goal Is to Not Quit - Courtland Allen of Indie Hackers
- #35 - The Technical Challenges of Measuring Gravitational Waves - Rana Adhikari of LIGO
- #34 - Elizabeth Iorns on Biotech Companies in YC
- #32 - Hosain Rahman on The "Defibrillator Experiences" of Jawbone
- #31 - Spotting Ecommerce Trends in Shipping Data – Laura Behrens Wu
- #30 - Artist Lauren McCarthy Will Be Your Home's Brain
- #29 - Jack Dorsey On The Books That Helped Him Succeed
- #28 - Prerequisites for Starting a Company - Phil Libin
- #27 - The CEO Who Pays Employees to De-Locate From the Bay
- #26 - Founders of Science Exchange, Goldbely, and The Flex Company Discuss Fundraising
- #25 - Baidu's AI Lab Director on Advancing Speech Recognition and Simulation
- #24 - Padmasree Warrior on Designing Autonomous Vehicles - With Anu Hariharan at the Female Founders Conference
- #23 - VMware Cofounder Diane Greene with Jessica Livingston at the Female Founders Conference
- #22 - Morgan DeBaun on Reaching 20M Millennials - With Kat Manalac at the Female Founders Conference
- #20 - Making Music and Art Through Machine Learning - Doug Eck of Magenta
- #19 - Blockchain Investing - Olaf Carlson-Wee and Aaron Harris
- #18 - Q&A with YC Partners at the Female Founders Conference
- #17 - Aileen Lee and Kirsty Nathoo at the Female Founders Conference
- #16 - Mark Zuckerberg on How to Build the Future
- #15 - IPFS, CoinList, and the Filecoin ICO - Juan Benet and Dalton Caldwell
- #14 - Ex Machina's Scientific Advisor - Murray Shanahan
- #13 - Scaling Growth - Gustaf Alstromer, Ed Baker, and Josh Elman
- #12 - How Should Business Schools Prepare Students for Startups? - Jeff Bussgang and Michael Seibel
- #11 - At The Intersection of AI, Governments, and Google - Tim Hwang
- #10 - Office Hours with Ali Rowghani
- #9 - Sam Altman and Reid Hoffman - From Startup to Scaleup
- #8 - Rick and Morty Writer - Ryan Ridley
- #7 - Jessica Livingston on How to Build the Future
- #6 - Office Hours with Kat Manalac
- #5 - An AI Primer with Wojciech Zaremba
- #4 - Elon Musk on How to Build the Future
- #3 - The Technical Advisor for Silicon Valley on HBO - Ed McManus
- #2 - Network Effects with Anu Hariharan
- #1 - Hiring Engineers with Ammon Bartram
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