GLP-1 Side Effects, Risks, And Who Should Actually Be Using It | Dr. Christle Guevarra

**Dr. Christle Guevarra** (0:00)
Throughout various parts of my life, since I can't figure out this whole calories, fat loss thing down, I am just going to focus on lifting weights and find, you know, joy in taking ownership of the fact that I can lift something heavy. It gave me a lot of confidence that I couldn't get from hunger, fat loss, you know, losing weight.

**Dr. Gabrielle Lyon** (0:23)
We are alive at a time that the landscape of medicine has changed. GLP-1s have been around for a long time, but they haven't been used. They have not been FDA approved for weight loss.
There has never been something more effective than these medications.

**Dr. Christle Guevarra** (0:39)
I feel like there's still a lot of a disconnect, especially with the way medicine traditionally is set up. Sometimes it can get a little hard to help with the behavioral change aspect of the GLP-1 use. And so I find that there are still a lot of people who are struggling with, how do I eat? How do I exercise? It seems like we could do a little bit better in providing that support when it comes to the behavioral change part.

**Dr. Gabrielle Lyon** (1:06)
What are some of the biggest challenges that they come in and say they've struggled with?

**Dr. Christle Guevarra** (1:10)
When somebody's eating to get in as much fiber to feel satiated and they still don't, I have to wonder, is that?

**Dr. Gabrielle Lyon** (1:26)
Dr. Christle, welcome to the show.

**Dr. Christle Guevarra** (1:28)
Thank you so much for having me.

**Dr. Gabrielle Lyon** (1:30)
Now, you are a family physician, and you also are trained in sports medicine. You are educating a lot on the use of GLP-1s, which we are going to talk all about that. We're going to talk all about fat loss.
And you're very interested in muscle preservation as well as performance.

**Dr. Christle Guevarra** (1:47)
Correct, that is correct.

**Dr. Gabrielle Lyon** (1:49)
Take me through what you are seeing right now in the landscape.

**Dr. Christle Guevarra** (1:51)
GLP-1 use, it seems like there's a lot of good things happening and there's a lot of things that are more cool. We could do a little bit better.
There's a lot more emphasis on resistance training across the board, which is, obviously, that's always awesome. And so women, I'm seeing a lot more women in the gym physically. So that is also amazing. And a lot more patients are just receptive to the fact of like, oh, I don't want this ozempic butt, so I'm going to get into the gym and lift something and challenge myself. I feel like there's still a lot of a disconnect where, especially with the way medicine traditionally is set up with clinic, with checkups once every four weeks, three months. I think sometimes it can get a little hard to help with the behavior change aspect of the GOP1 use. I find that there are still a lot of people who are struggling with, how do I eat? How do I exercise? I just take this shot and I have these side effects, and I'm going to wait X amount of weeks till my next follow-up appointment to bring them up.
The medical system in which we're in the traditional practice model, it seems like we could do a little bit better in providing that support when it comes to the behavioral change part.

**Dr. Gabrielle Lyon** (3:20)
You've actually been really public on your Instagram, social media, talking about your own journey with GLP-1 News. Do you think that obesity five years from now, not even 10, do you think we're still going to be struggling with obesity?

**Dr. Christle Guevarra** (3:34)
I think we're going to be struggling with it a lot less so. I think there are still going to be people who are hesitant to take these medications just because of whatever, you know, this, it still feels like too good to be true because we have a long-standing history of diet medications that have not been so healthy for us and, you know, have been recalled by the FDA.
Back in the day, the rainbow pills in the 1950s and 60s. So, you know, people still have that hesitation towards, you know, drugs that are, you know, FDA approved. And people, you know, will still hesitate. But I think, overall, population wise, I think that obesity is going to decrease.

**Dr. Gabrielle Lyon** (4:21)
And again, you train in sports medicine, family medicine, you were on the front lines. There has never been something more effective than these medications.

**Dr. Christle Guevarra** (4:32)
Correct. This is a new, this is, you know, a new breakthrough. And it's only going to get better, especially with the drugs that are still in clinical trials, and they're coming down the pipeline. But, you know, after semaglutide, Ozempic, Wigovia became FDA approved for chronic weight management. It's just been, you know, it's just only going to go up from here.