Bryan Johnson & Kate Tolo On Curing Their Incurable Diseases, Addressing The Disparity In Women's Health & The Don't Die Mission
The Rich Roll Podcast
September 21, 2026
Bryan Johnson and Kate Tolo are entrepreneurs, partners, and the subjects of the Netflix documentary "Don't Die." This conversation explores the couple's challenge to a presupposition around our mortality.
Speakers Rich Roll, Bryan Johnson, Kate Tolo
TopicsSelf-ImprovementEducationHealth & Fitness
Rich Roll (0:00)
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Bryan Johnson (1:27)
If we are to be Don't Die, we both have to cure our incurable diseases. So either they get us or we get them.
SPEAKER_3 (1:33)
Anti-aging entrepreneur Bryan Johnson revealed a recent diagnosis of autoimmune gastritis.
Bryan Johnson (1:38)
Kate Tolo is the most measured female in history.
Rich Roll (1:42)
One of the sharpest content minds, Kate pitched Bryan, what if the science experiment was done in public?
Kate Tolo (1:47)
We're spending $2.6 million on my protocol. I was like, oh yeah, I think I have suspected endometriosis. Bryan hears about it and I was diagnosed in something like 42 days. Women typically take six and a half years to get a diagnosis.
Bryan Johnson (2:01)
I think it's possible that we have a cure within like six months. This has never been done before. We've done all of this in four weeks time.
Rich Roll (2:09)
There's a perception that this is about you wanting to live forever.
Bryan Johnson (2:13)
I can't understand what living forever means. I simply want to say yes to existence.
And what I really concluded is that.
Rich Roll (2:26)
Super nice to be here, you guys. Thank you for inviting me into your beautiful home, into the sanctum.
I'm excited to talk to both of you together. And my first question really is for Kate, like I just want to know, like what is it actually like to be in a relationship with this lunatic?
Kate Tolo (2:48)
To look over and you're just smiling.
Bryan Johnson (2:49)
Yeah, you just have at it.
Kate Tolo (2:51)
Yeah, it's a lot. It's definitely different.
Bryan is a unique, special human being, and I've known that since day one, since the first moment I looked into his eyes. And honestly, I feel like it's out of my control. I don't think I am in charge of whether or not I love Bryan. My body just does, and so.
Rich Roll (3:12)
What is your relationship history prior to this? In terms of other guys that you dated and the delta between that and the experience of living with Bryan?
Kate Tolo (3:23)
Yeah, I think Bryan's just one of a kind. So I would categorize myself generally, both in relationships, but also lifestyle, how I think about the world as a fairly normal, average bell curve person prior to meeting Bryan. And so even in just the way I live life now, it's entirely different.
Rich Roll (3:42)
Initially, you came in as an employee, right? Like you were working here for quite a while, right?
Before the relationship blossomed. What attracted you to wanna be in his employee to begin with? Like what was it inside of you that like wanted to be part of this whole thing?
Kate Tolo (4:00)
It was his neurotech company that I fell in love with so deeply. I was 21, I just moved to New York. I had grown up in a small town with immigrant parents, so I didn't have a ton of exposure to like, what is an engineer and what's a consultant? Those words just didn't mean anything to me. I got to New York. I was working in fashion because I learnt how so when I was eight years old. And I started to see the world for the big space that it is and learnt about AI. This is back in 2016
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