Best Peptides, Stem Cells, Testosterone & Exercise Hacks - Biohacking Roundtable - #1148

Chris Williamson (0:00)

People of the UK and Ireland, if you are coming to see me on tour, I want to hear from you. I want to know what problems you're dealing with, your worst first date, and any questions that you've got for me. And I will be bringing some of you up on stage to talk about it. So if you're coming to see me on tour this October, go to chriswilliamson.live slash stories, submit them and I might see you with a mic in front of your face very soon. ChrisWilliamson.live slash stories.

Everyone, tell me what peptides you're on. That's all I care about.

Ben Greenfield (0:26)

Let's go. Which day of the week? Which time of the day?

I view peptides as a little bit more of like a condiment that's in your refrigerator that you might use for a specific reason and don't follow an exact protocol every day. For example, when I travel, I use thymus and alpha 1, which I'm on right now, as you can tell, for the immune system. Yeah. I keep around BPC 157 and TB 500 for injuries. I run a couple of times a year, a tessamarylin, ipamarylin with CJC 1295 cycle for growth hormone.

Those are the biggies. C-max and C-link intranasal. C-max is a little bit more of like a cognition, brain-derived neurotrophic factor booster, and then C-link is more of like an anxiolytic. So, kind of an up or downer. It's like my version of Valium caffeine. Yeah.

Brigham Buhler (1:29)

What he said.

Ben Greenfield (1:30)

Yeah.

Brigham Buhler (1:31)

And pretty much that protocol I agree with. And I tell everyone the answer is not at the bottom of a peptide bottle. Like diet, lifestyle, nutrition, living by the principles first. These are like additives that can help optimize your health, especially with our food sources and how stripped they are of the nutrients.

The only compounds that I think I take that you didn't discuss is IGF LR3. I don't know if you've ever messed with that. Insulin Growth Factor LR3. So a lot of people take growth hormone historically, but the reason they were taking growth hormone was in an effort to get all the therapeutic benefits that growth hormone gives you when it converts to IGF. And so if you were to use the peptide IGF, you get all the benefits of growth hormone, but with a much better safety profile that will not impact your natural growth hormone levels.

And so that's why I'm a huge fan of IGF.

Ben Greenfield (2:19)

Does it have like a similar, like pure HGH, you get a little bit of almost like a glucocorticoid response where there's a surge in cortisol, your resting glucose tends to be higher, a lot of people don't sleep as well at night. Because it goes on a downstream pathway, do you skip out on a lot of that?

Brigham Buhler (2:37)

Yeah, you do skip out on a lot, but bigger than that is you're not impacting your natural growth levels. So, you know, you're still in your four, I'm in my 40s, 46, so I want to be cognizant of that. But anytime I come off, like, so I'll go on for four to six weeks. And then I, when I come off, I'll cycle on to CJC and some of the other things you discuss just to boost my natural growth hormone levels.

Dr. Gabrielle Lyon (2:57)

So I have the simplest protocol here, sounds like. I will microdose GLP-1 once in a while for inflammation. I think there's going to be new emerging research. I was actually at the Protein Working Group Summit 3.0. And that is like the Oscars for nerds and protein scientists.

I just, invitation only, a hundred of the finest scientists that are doing protein research. And there were topics of discussion, like what are the challenges that we face. But more importantly, I sat with Arne Astrup, who discovered GLP-1's impact on appetite. So he was essentially responsible for what we now have as this obesity, now not called obesity sarcopenic epidemic, GLP-1 use, which again, I'm totally for GLP-1s. But that is my- Cool.

Ben Greenfield (3:50)

You said you're microdosing it for inflammation?

Dr. Gabrielle Lyon (3:52)

Yes. And there is going to be new emerging research that it is going to have an impact on cancer, they believe.

That low dose GLP-1, we don't totally know. He believes it's through inflammation. And this was the guy who discovered GLP-1's effect on appetite.

Chris Williamson (4:09)

How do you know that it's not just a reduction in the turnover of food? We don't. We don't. So all of this could just be people eating less. Eating less cancer-causing food. It could be.