The State Of Gene Editing - EP 37 Eryney Marrogi artwork

The State Of Gene Editing - EP 37 Eryney Marrogi

Core Memory

October 8, 2025

We have a proper treat this week. Core Memory special correspondent Eryney Marrogi comes on the pod. Marrogi is a scientist and soon-to-be doctor who has followed the rise of the gene editing tools at humanity’s disposal.
Speakers: Eryney Marrogi, Ashlee Vance

Topics: Technology, Science

**Eryney Marrogi** (0:00)
San Francisco has like too many billboards of like-

**Ashlee Vance** (0:03)
On the freeway.

**Eryney Marrogi** (0:04)
Yeah, like agentic workflows for like things I didn't know that you could have a workflow for. Yeah.

**Ashlee Vance** (0:10)
Yeah, well, I mean, this is the great San Francisco tradition is the billboards on the 101 where you understand what is the next new thing.

**Eryney Marrogi** (0:20)
I'm hoping to like pay like pilgrimage to the Cluely billboard, like whoever that is. I would like to see that with my eyes, but I don't know if it might not happen.

**Ashlee Vance** (0:30)
I felt like that was working for him for like a week.

**Eryney Marrogi** (0:33)
And now it's. It turns out, yeah, the amount of goodwill you can get on Twitter is like pretty limited.

**Ashlee Vance** (0:42)
The shtick, they need a new shtick. Yeah, the billboards are funny though, because you can, I always use this as my hype cycle gauge. Because you go, it's like after, when the AI thing started to take off, it's like there's two or three and then.

**Eryney Marrogi** (1:00)
Now, I didn't see like a single injury law firm.

**Ashlee Vance** (1:06)
No.

**Eryney Marrogi** (1:06)
Not a single one.

**Ashlee Vance** (1:07)
It's like every billboard is an AI billboard. And then like you said, if you're not from here.

**Eryney Marrogi** (1:11)
It's jarring.

**Ashlee Vance** (1:12)
Right. Because it's not just like, oh, it's open AI and Claude. It's like some super idiosyncratic AI book flow.

**Eryney Marrogi** (1:19)
This is like shoe.ai. We do AI shoes.

**Ashlee Vance** (1:24)
There's one, I don't know if they still have it, but right as we're getting in to San Francisco, it's like renting GPUs and stuff. Like, where do we live, man?

**Eryney Marrogi** (1:31)
SF computer. Yeah. It's good. I like it. I mean, Vermont doesn't have any billboards. There's zero billboards in Vermont. It's like a law.
So to go from like that to this, I'm like, wow, this is...

**Ashlee Vance** (1:44)
Yeah.

**Eryney Marrogi** (1:45)
It's very drawing.

**Ashlee Vance** (1:45)
I think there's one that's like pro-Israel and then right behind it is like pro... No, I think that they put like a pro-Palestinian one up and then some Israeli group put the right behind it.

**Eryney Marrogi** (1:59)
Well, at least they're balanced. It's like a balance, like a yin and yang type thing.

**Ashlee Vance** (2:02)
Yeah.

**Eryney Marrogi** (2:03)
It's good to have balance with these things.

**Ashlee Vance** (2:06)
Okay. We'll jump in. I'm going to take a crack. You're going to have to help me on the last thing.

**Eryney Marrogi** (2:13)
Yeah. Do you want me to do it for you? Well, what are you going to do?

**Ashlee Vance** (2:18)
You grade me.

**Eryney Marrogi** (2:19)
Okay.

**Ashlee Vance** (2:36)
Eryney Marrogi.

**Eryney Marrogi** (2:37)
Eryney Marrogi.

**Ashlee Vance** (2:39)
Eryney.

**Eryney Marrogi** (2:39)
Eryney.

**Ashlee Vance** (2:40)
Eryney.

**Eryney Marrogi** (2:40)
It's very simple. It's like Eryne-ay, very simple.

**Ashlee Vance** (2:42)
Eryne-ay. Now, when I listen to this a bunch of times.

**Eryney Marrogi** (2:45)
No, it's okay, it's okay, it's okay.

**Ashlee Vance** (2:47)
Eryney Marrogi.

**Eryney Marrogi** (2:48)
Marrogi, yeah.

**Ashlee Vance** (2:49)
But the O is almost a U.

**Eryney Marrogi** (2:52)
Marrogi is good, yeah. Marrogi is good, yeah.

**Ashlee Vance** (2:55)
Where's the O from?

**Eryney Marrogi** (2:56)
Yeah, so my mom is Ukrainian, and my dad is from Iraq.

**Ashlee Vance** (3:02)
Okay.

**Eryney Marrogi** (3:02)
And so the last name is Iraqi. I can say the first name is Ukrainian. If I want to simplify it, it's Ukrainian. We'll do that.
But yeah, so yeah.

**Ashlee Vance** (3:12)
Do you get Ernead a lot?

**Eryney Marrogi** (3:14)
Yeah, I get it all. Yeah. So a very common thing is I'll introduce myself to a patient in the hospital. I'm Eryne, I'm working on your medical team, and they're like, okay, Eryne. It's fine, I just let it go.
But I get Ernie, I get it all. Whatever you think I could get, I've gotten it.

**Ashlee Vance** (3:34)
Well, I'm lying, I am a woman.

**Eryney Marrogi** (3:38)
I'm going to be honest. So like a year ago, I was like, yeah, this Ashlee woman, she just tapped into everything.
I had read an article that you wrote, and I feel like finally, I was like, I'm going to like, what is this woman's like? How did she get into this? And then I obviously corrected. Yeah. It sort of broke my brain a little bit.

**Ashlee Vance** (4:01)
This lets me know my video show is not doing well enough.

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