The GLP-1 Warning No One Is Giving You: Dr. Stacy Sims on Muscle Loss, Birth Control, Perimenopause & the Female Physiology Research That Was Never Done

**Jonathan Cohen** (0:00)
Mayim Bialik's Breakdown is supported by Helix Sleep.

**Mayim Bialik** (0:03)
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**Stacy Sims** (1:09)
We are now in a time in history where there are so many people that are overfed and undernourished.

**Mayim Bialik** (1:15)
Two billion people worldwide have micronutrient deficiency.

**Stacy Sims** (1:19)
Eat a wide variety of foods, 30 different plants a week.

**Mayim Bialik** (1:22)
30 different plants a week?

**Stacy Sims** (1:24)
There is an endemic happening.

**Mayim Bialik** (1:31)
For every 10 pounds that you lose on a GLP-1, up to four pounds can come from muscle.

**Stacy Sims** (1:38)
When people are talking about weight loss, what do we have to gain with putting muscle on? We have more control over what we're eating, better sleep, better immunity, better blood glucose control, better cognitive function. We have the capacity to gain a higher quality of life for whatever age you are.

**Mayim Bialik** (1:54)
Dr. Stacy Sims is an exercise physiologist and pioneering nutrition scientist.

**Stacy Sims** (1:59)
My frustration of being an athlete and researcher in academia, noticing that there was no real representation of women. I wanna close that gender gap.

**Mayim Bialik** (2:07)
What happens to the amygdala when you give oral contraceptives at a young age?

**Stacy Sims** (2:13)
We see changes that are not reversible. That increases the capacity for anxiety and fear.

**Mayim Bialik** (2:18)
Tell us five things that every woman should be doing for her health. Hi, I'm Mayim Bialik.

**Jonathan Cohen** (2:33)
And I'm Jonathan Cohen.

**Mayim Bialik** (2:34)
And welcome to our breakdown. Today we're going to be tackling some of the biggest myths and trends in the health and nutrition industry, specifically as they relate to female physiology.

**Jonathan Cohen** (2:48)
And if you're thinking, I'm not a woman, maybe I'll turn this episode off, stay tuned because we cover things that totally blew my mind from the huge dangers of GLP-1s to the real truth about creatine, the biggest mistake people are making, and you're likely drinking water totally wrong.

**Mayim Bialik** (3:10)
This episode also covers things that many of us take for granted, like our understanding of why people go on birth control, why people lift heavy weights, how to protect your brain, how to live a longer and more vibrant life.
These are things that impact men and women differently, but understanding the differences in physiology can make a huge difference. And we're speaking to Dr. Stacy Sims, the author of ROAR, a really, really fantastic book. Match Your Food and Fitness to Your Unique Female Physiology for Optimum Performance, Great Health, and a Strong Body for Life. But as we said, we're not just going to be talking about how these things impact women. We're going to be talking about the differences in male and female physiology, and how so many of the trends that you might be following, you're actually approaching in the wrong way. We're also going to talk about a deficiency that impacts 2 billion people worldwide. And when you hear the list of symptoms, you might be surprised to find you may be at risk for this deficiency. This episode is also in honor of Women's Health Month. We could not think of a better guest to have for this very special episode than Dr. Stacy Sims. So without further ado, let's welcome to the Breakdown Dr. Stacy Sims.
Break it down.

**Stacy Sims** (4:28)
Thanks for having me. I'm excited.

**Mayim Bialik** (4:30)
We're very excited to talk about Roar. And I'm really like your target audience for this book and this message.
And I noticed that on page 50, there is a crushing it as a 50-year-old vegan. And I thought, Stacy, you didn't need to put me in your book. That is so embarrassing.