Episode #161: What’s Making You Sick: Cholesterol, Mitochondria & Chronic Disease Featuring DR. WILL COLE!!
The Dylan Gemelli Podcast
September 9, 2026
What if the reason you feel tired, inflamed, foggy or simply OFF actually begins at the CELLULAR LEVEL?
Speakers Will Cole, Dylan Gemelli
TopicsAlternative HealthHealth & Fitness
Will Cole (0:00)
But healthy people don't need pharmaceutical drugs. It's not a great business model to get people healthy for a certain industry.
Dylan Gemelli (0:05)
Funny story here, maybe not so funny. In prison, I learned that ibuprofen was the answer to everything.
Will Cole (0:11)
I think we all need to do it, especially in this age of AI. To be pro-human is to get out there, to reach out to people, because there's a loneliness epidemic, I think it was out of MIT, that found that people that use AI to write essays, which so many people do, it was associated with a 55% decrease use of the brain.
Dylan Gemelli (0:28)
Dr. Cole, are you indicating that crushing LDL is not optimal for cellular health?
Will Cole (0:32)
I know, it's shocking. I would say that's one of the worst things you could do. It's probably easier to change someone's religion than the foods they eat. People become so ideologically tribal about it, right? They make it their personality.
Dylan Gemelli (0:44)
Do you want to know why nothing seems to help you with constant cravings? GLP-1 is the hunger hormone that everyone's talking about, but your gut was designed to make it on its own, however it needs the right signal. Bitter receptors in your gut and mouth are directly tied to GLP-1 release, and most modern diets are extremely low in bitter foods, and so this natural pathway rarely gets activated, but have no fear because I found the answer with Just Thrive Digested Bitters. Just Thrive Digested Bitters deliver concentrated bitter botanicals that activate receptors in your gut, encouraging your body to produce GLP-1 naturally, supporting healthy digestion, comfortable fullness, and a balanced appetite without any synthetic inputs. No bitter taste required. The bitter receptors that matter most for GLP-1 signaling and digestive support aren't just in your mouth, they line your entire GI tract. So when the capsule dissolves in your gut, the bitter botanicals activate those receptors, same signal, same response, zero bitter taste. Right now, Just Thrive is offering my listeners something special. When you start a 90-day Just Thrive probiotic subscription, you'll get a free 90-day supply of their new digestive bitters, and that's a $90 value. So visit justthrivehealth.com/dylan to claim your free digestive bitters with your first 90-day probiotic subscription today. All right, everybody, welcome back to The Dylan Gemelli Podcast. So as you can see, I am back in Nashville. I'm actually in our good friend, Dr. Josh Axe's studio, and I will tell you, today's already been amazing. I have been working on this interview, well, since November, since I met my guest back then. We've been trying to figure this out, and it's been a long time coming, but we know God's timing is impeccably perfect, and there was a reason for this, and I feel absolutely amazing about the discussion that we're about to have, and it is, like I say, a real honor to have my guest here today.
He is one of the biggest beacons of light, not just in biohacking, just in health and wellness, and the whole entire space. Now, he's a leading functional medicine expert, and he consults people around the globe, and he's one of the most recognized functional medicine doctors and experts that you will ever see. He's got a new book coming out. It's called Heal Your Cells. I have already been privy and blessed to read some of this. He's got one of the best podcasts known to man. I know that you've heard of it. It's The Art Of Being Well.
I can't give him enough accolade. There's only so much that I can say before we get into this. I am honored, pleasured, and just cannot wait to introduce my guest, Dr. Will Cole.
Will Cole (3:33)
Thanks, man. I need you as my hype guy on the daily. Just like as my morning meditation mantra, I just want Dylan to speak in my... I'm also married to two golden doodles and two kids, an egret, I'm five, long walks on the beach.
Dylan Gemelli (3:52)
I love it. I'm known for my intros, bro. I love it. I get lucky here and there on what I do. I love it. Now, man, look, like I said, we've been trying to set this up for a while.
Will Cole (4:02)
Yeah, I apologize. I'm hard to nail down sometimes. I'm just like an introvert that lives in the woods. Like you said, it's divine timings, God's timings.
Dylan Gemelli (4:11)
It is. I live through a calendar anymore and I go seven days a week and still can't do things properly, so I get it. But it is, I meant what I said, it is a real honor to sit here and speak with you today because I respect so much of what you do. It's not just the knowledge that you carry. It's the will, so to speak, on how you do things and what you overcome, what you deal with daily, and your drive to improve people's lives. Now, functional medicine, for me, is everything.
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