Episode 1040: AMD Is a $1 Trillion Bubble, Ozempic Is About to Collapse, Novo Nordisk Stock
The Shkreli Pill
September 23, 2026
In this episode, Martin lays out his bearish thesis on AMD and explains why he believes expectations surrounding AI growth have pushed its valuation to unsustainable levels.
Speakers Martin Shkreli, Keith
Martin Shkreli (0:00)
We have a bunch of things going on today. Novo Nordisk, the Ozempic maker, is hosting their Capital Markets Day. QBioPharma had some data. We traded a little bit of Q this morning, shorted mostly.
What else is going on?
Greenland, we own Greenland now. That's a big deal, big time Greenland. I'm at 95,000 YouTube subscribers. Let me get 5,000 more and let me get that plaque. Make sure you hit subscribe. I think you get notified anytime I go live, which is obviously crucial, crucial. Better. Very crucial. Bonjour, love. Howl, love. Thoughts on howl? Have you been investing in biotech? I talk a lot about biotech, brother. Spent 25 years in biotech. Still short on IonQ. Again, you gotta learn the lingo. You come at me, speak English, and you gotta learn the slang of the markets. You don't say, are you still short on IonQ? You can't be short on a stock.
You don't say, are you still long on...
Just remove the on. So delete your comment, retract the statement, and try again. I've been telling Keith that too, man. Oh, we gotta get Keith Pienelle up on the screen as well. We haven't been doing that either.
We gotta update. We got crazy, crazy numbers in Keith's. But we have to, we have to... You opened up Twitter, there's all this stuff. Yeah. There's all the LGBT community activities that you do. Nothing wrong with that. And just, it's cool that you're active in that community. Gotta support you people. I am still short IonQ, although I get in and out of it a lot. And I was short on Friday. It went down. I got out of a lot of it. So, but I think it's, you know, we should do a refresh on IonQ, honestly. Just go through the numbers. They've obviously bought a lot of crap. So, you know, it feels like an even bigger short now that they've bought all this trash. But I feel like we have to at least analyze it. Give the devil their due. Keith ETF Wen. Genomic stocks or biotechs? The problem with biotech and genomics is you can't really get long term exposure easily without taking crap loads of risk in companies. Agent loops. We'll have more to say about that later in the week, actually. But the problem with some of those loops is you're really talking about a lot of expense. So we're putting out an API in the near future, but it's going to cost an enormous amount. Hey, good morning.
It's just going to be so expensive that there's not going to be an ability to afford it for most people. Thank you so much.
So it's just, what are you going to do about shorting stock right now? I'm just going to get our position on it without talking about it just yet, but it's going to be a fun one.
Q, Q has dropped. I think Q is going to drop further. It's kind of a weird situation, but I don't think it's going to go up. Semis are ripping, Intel's up like 6%. Libbutan said that they can't meet half of their demand, which is wild. Moderna is up? Should short that. Oh, my homies hit one turn. So yeah, their Greenland stocks are up. Those are the ones we're talking about.
Um, really kind of... Wait, can I say that word? Really stupid system, system prompt, incorrect. No, um, Greenland stocks. I'm glitching. The matrix is getting me. Greenland stocks are up. There are no Greenland stocks, though. It's all fake. So we're shorting those. Good for you, Josh. I'm glad you didn't buy. Yeah, I can put that in paid. And they're off. Markets open.
Keith (3:30)
Oh, oh, all right.
Martin Shkreli (3:35)
Donk donk donk. Spontane. That guy's chat. Let's see what's going on. Intel 1 Where's Intel? 187? Nope. Where is it? 119
Almost 120 Having some bunk moments this morning. I think Q's gonna, like, Q gonna collapse. Dandisk 1800 My micro. 1048 3%. Supposedly, DRAM prices may be dropping. Twist dropping a little bit. A lot of drama over Twist. Trimmer maker Twist. Novo's capital market stay.
Oh yeah, I'm supposed to use this, this thumbnail I has. But I should have somebody else do that for me. Too lazy. What's that? I don't know. It's your call, buddy. I think it's...
I'm sort of bullish. I don't know. God, I hate this so much.
Again, with the long on. It's not long on. There's no on. What's the part of speech on is? Any good college student would know this. What part of speech is on? On is a preposition, but it can function as an adverb or adjective. Don't even know English. This guy knows how to speak to Kodak Black, though. Sniper gang.
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