#376 My Top 10 Supplements, How Much Glycine and Aging Test Update - Q&A

Siim Land (0:00)

Welcome back to the channel, my name is Siim Land, and today we're doing another Q&A. I know it's been a very long time since the last time we did this Q&A, but we're back with this right now. And if you want to ask me a question in the future, then make sure you follow me on Instagram. I'm doing the Q&A polls in the Instagram stories there. First question is about any updates to the True Diagnostics Age Speed Test that I did a few months ago for my first test. The score for the Speed of Aging was 0.62, which is one of the slowest in the world, and it actually would rank me at the Rejuvenation Olympics in the top leaderboard. Now, I need to wait six months from the first test to do the third test. You need three tests to categorize yourself into the Olympics. And that's the rules. And I still need to wait at least until mid-October for me to do the third test. Now, I did want to do the second test, but I actually had COVID in the meanwhile, short-term COVID, and I had an infection. And any kind of infection, whether that be COVID or whatever other type of sickness, illness, is going to mess up the results because your biological age has been seen to increase during the sickness and infection.

So that's why I haven't done the second test yet. That would be worthwhile to do for the Olympic leaderboard. Yeah, I need to wait a little bit more. And I'm probably going to just do the second and the third test around the same time in October or the late September, somewhere around there. I definitely need to wait at least until October 13 or 14 to do the third test. But the second test, I'll do probably a bit before that. This episode is brought to you by Alitura Naturals. Alitura brings you the best natural skincare products for radiating skin and anti-aging. Regular skincare products are full of ingredients and fillers that actually cause more harm than good. Alitura uses only active ingredients, sourced and handcrafted in Hawaii. Their products contain zero fillers. The Alitura Night Cream received the 2021 Clean Cert Beauty Awards for best face cream. Alitura also has skin moisturizers, clay masks, serums, and cleansers. Head over to alitura.com and use the code Siim, S-I-I-M, for a 20% discount. Next question is, how much glycine would you need per kilogram of human weight?

So, you know, I did make a recent video about the GlyNAC supplementation, glycine, and NAC. So the combination of these supplements has been found to reverse hallmarks of human aging and improve many of the age-related outcomes, like muscle strength, gait speed, cognitive function, and body composition. So it is actually one of the most proven or supplements in humans, in my opinion. Like there's many other supplements that don't have pretty much any human data or human clinical evidence, but the GlyNAC combination apparently has, actually like multiple human studies, at least like five or six of them, that shows kind of the similar results. Now, those studies generally use around 100 milligrams of glycine per kilogram per day. And for NAC, it's 98 milligrams per kilogram per day. So for me, I weigh 80 kilograms. Then for me, I would need eight grams of glycine at least to get those benefits and 7.8 grams of NAC. Of course, you know, you can even dispute that because I'm 29 years old, and we don't know whether or not the GlyNAC supplementation would have any benefits for people my age. It certainly has benefits for the elderly people, because those individuals, the older you get, the lower your glutathione levels are going to be, which will then increase the oxidative stress and the inflammation and just overall burden on the system. Whereas if you're young, your glutathione levels and antioxidant defense levels are much higher. So we don't even know if it would, or there's no evidence to suggest that the GlyNAC would have any benefits for someone in their 20s or 30s. But I do take it on some days, especially if you're about to catch a cold, or something, then you can just take that to support the glutathione and antioxidant defense system. Now, the issue with that dose is that you would actually need significantly more glycine than that. You know, the 7.8 grams of NAC per day is quite a lot.

I haven't taken that large dose ever personally, but it would probably be warranted for the elderly people if they're trying to raise the glutathione levels, because they see that 2.4 grams of glycine and NAC each doesn't raise glutathione in the elderly, but 4.8 and 7.2 grams does. So for the elderly, you do need a larger dose of glycine and NAC to see the effect on glutathione levels, whereas 2.8 grams or 2.4 grams, it doesn't appear to be enough to see that effect. So if you are trying to raise the glutathione with Glynak, then you need a moderate to high dose. So at least 4.8 to 7, even 8 grams of Glynak and of glycine and NAC each per grams.