Peter's key takeaways on liver health, heart rate variability, AI in medicine, klotho, and lactate metabolism | Quarterly Podcast Summary #2

**Peter Attia** (0:10)
Hey, everyone, welcome to a sneak peek, Ask Me Anything, or AMA episode of the Drive podcast. I'm your host, Peter Attia. At the end of this short episode, I'll explain how you can access the AMA episodes in full, along with a ton of other membership benefits we've created. Or you can learn more now by going to peterattiamd.com/subscribe. So without further delay, here's today's sneak peek of the Ask Me Anything episode.
welcome to another special AMA episode of The Drive. Today's episode will be the second of what we're now calling the quarterly podcast summary. We did the first episode of this back in June and the feedback was overwhelmingly positive. In fact, I don't think we've ever received more feedback on the day of a podcast release than we did for the quarterly podcast summary number one. So it's no surprise that we're going to bring this back and continue to do it because again, people seem to really like this and quite frankly, it's a lot of fun for me. These quarterly podcast summaries will look back at recent episodes released typically over the last quarter and I'll discuss what I learned from the interview and what I think were some of the most important insights as well as any changes in my behavior or thinking that resulted from the interview. In today's episode, we will cover the interviews that I did with Julia Wattacheril, Joel Jamieson, Zak Kohane, Dena Dubal, and George Brooks. Throughout this, we speak on topics such as liver health, heart rate variability, the emergence of AI and its potential impact on medicine, the gene and protein clotho and its relationship to Alzheimer's disease and its potential to treat these conditions and all things related to lactate. If you are a subscriber and would like to watch the full video of this podcast, you can find it on the show notes page. If you're not a subscriber, you can watch a sneak peek of the video on our YouTube page. So without further delay, I hope you enjoy this special quarterly podcast summary AMA of The Drive.

**SPEAKER_1** (2:18)
Peter, welcome to another AMA. How are you doing? Good.

**Peter Attia** (2:21)
Thanks for having me back.

**SPEAKER_1** (2:23)
You're always welcome. So this will be the second episode that we've done like this, which is our quarterly podcast summary. We released the first one back in June, received really positive feedback. People really liked it, wanted us to continue to do it. So today, we're going to look at previous and recent episodes of The Drive. As we look at them, we'll look at what your key takeaways are from the episode, along with anything you changed as a result, whether behavior, whether your mind, whether how you're thinking about things, anything of that nature. So in today's episode, if all goes well, we'll cover topics such as the liver, liver health, heart rate variability and training, AI and medicine, clotho and Alzheimer's disease, lactate, and more. So with all that said, anything you want to add before we get rolling?

**Peter Attia** (3:16)
Only that I was so pleasantly surprised at how people took to the first episode of this quarterly summary that we did in June and said, hey, that was the single most valuable piece of content you've ever put out. What I thought was nice that there were people who said, look, these are episodes I didn't listen to, and now I just got the summary, or these are episodes I didn't listen to, and I got this summary which made me go back and listen to the actual episode or hey, I did listen to it, but honestly, it's just hard to remember everything. So I think when we sat here three months ago and recorded the first one, we were sort of like, well, we hope people like it, and if you don't like it, we certainly won't waste anyone's time doing it, but I think it might be the most emails we've ever received for a single podcast with people saying, this was fantastic, please do it more. So it's really nice to hear that, and obviously, it's our pleasure now to just make this a regular part of what we do each quarter.

**SPEAKER_1** (4:08)
Yeah, and you kind of hinted at there too is, it's important to note these aren't replacements for listening to episodes. A lot of times they're good either refreshers, good to figure out to go back and listen to, or just to kind of put the pieces together based on what you heard. And so with that said, first episode we will look at is the one with Julia Wattacheril on liver health, liver disease, NAFLD, MasLD, everything as it relates to the liver. So you want to kick us off?