Can AI Help Us Live 250 Years? The Future of Human Longevity

**Shekhar Natarajan** (0:00)
What the hell am I going to do if I lived for 250 years?

**Kevin Brown** (0:09)
Orwell was an optimist, because he never understood the power of machine learning.

**Jason Silva** (0:18)
I would describe myself definitely as a protopian or a techno-optimist.

**Natalie** (0:28)
So I'm really interested in how technologies shape our behaviors, our relationships, the way that we can see with ourselves, what's possible.

**Shekhar Natarajan** (1:00)
She touched it every morning before sunrise, a small gold ring, the only evidence anyone had ever chosen her. Then one fine day, she took it off. For me, a boy with no shoes, no future anyone could see, no proof he was even worth the price. My mother didn't pawn a ring that day. She pawned the only story she had that mattered to her. And she buried on a story that didn't exist yet. That was my story. I grew up in a single room in South India, in the slums. Dirt floors and walls that couldn't keep out the rain or the doubt. But my mother never looked at those walls. She never looked past them. That's not hope, because hope waits. She chose a direction and walked towards it. That's called orientation. Fire didn't ask our ancestors if they were ready for it. Neither did electricity or internet or the splitting of the atom. The future never asks us the permission. Right now, someone is designing the world. Your grandchildren are going to inherit. What would you give up to live long enough to meet your great, great grandchildren? What would you give up to never forget your mother's face?
What if the future offered you everything that you ever wanted, and it costed you everything that you had? My mother couldn't read. She couldn't plan. She couldn't prepare. But she knew what every futurist had forgotten. The future belongs to those who face it. Not the ready, but the ones who are oriented towards it. This show won't describe the future for you. It will drop you right into it. And ask you questions that are thought provoking. Who will you be when you get there? What will you hold on to? What will you let go? What will you pawn and for whom? My mother is gone now. But every morning, I think about a woman touching a gold ring in the dark, choosing a direction, choosing to believe. She couldn't have imagined the machines that think. Or lives stretched beyond two centuries. But she gave me something no algorithm would ever replicate. The courage to face what I cannot predict. This is Tomorrow Today. The future is already here, walking towards you. Turn and face it together.
Thank you, Four Seasons Hotel. I'm deeply thankful for making the space ours for today. Thank you so much. In July, 2024, researchers at Imperial College and Duke University gave elderly mice a single injection. It blocked one protein. The mice lived 25% longer, not just alive, but it was healthier, stronger, fewer cancers. Google just paid $571 million to license the technology. Human trials are already underway. In May 2025, Max Planck Institute combined two existing drugs. The mice lived 35% longer. Harvard's David Sinclair predicts an age reversal pill by 2035 100 bucks a month. Take it for 4 weeks and get biologically younger. Can you believe that? The longest verified human lifespan is 122 years. But Sinclair believes it could double. So I am not looking at 35 years anymore. I may be looking at 250 years. 250 years means 7 different careers. It means you are going to see great, great, great grandchildren, and they will be probably older than you. Till death do us apart, suddenly means 2 centuries of marriage. Would you take the pill? If death gives meaning, what happens when death becomes optional? My mother lived 70 years. She pawned her wedding ring for my education. What would she say if I lived 3 times her lifetime?
Would that honor her sacrifice or somehow diminish that? I came to this country with $34 in my pocket. I built technology for Fortune 500 companies. I filed hundreds of patents. But I have never faced a question like this in my lifetime. What the hell am I going to do if I lived for 250 years?
And that science isn't coming. It's already here. In this episode, we explore exactly that. Not whether we can live longer, but whether we should. And what it means for love, for purpose, for meaning itself. Because when the clock we've been always racing against, just stopped ticking. Welcome to the inaugural show of Tomorrow Today. I'm super excited to have great guests. In fact, the purpose of this show is to evaluate the technology that is already emergent amongst us. And what does it mean to the society in general? For my amazing guest, I'd love for you guys to introduce yourself, Jason, Natalie and Kevin, in that order. Why don't you introduce yourself, Jason? You are a phenomenal, prominent figure and a celebrity. I'm so glad to have you, but I would love for my guests to hear in your own words, like who you are.